Natural progression of meningeal lymphatic dysfunction in APP/PS1 mice creates a critical window for Alzheimer’s disease intervention
Lymphatic functional decline starts at 6-months old, providing a critical timeframe for early AD intervention. Our findings underscore the value of the APP/PS1 model for studying lymphatic clearance mechanisms in AD.
Authors
- Zilong Shen (ORCID: https://orcid.org/0000-0003-4333-1793)
- XIBIN ZHOU
- CHUNXIANG ZHOU
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Published
- 2025-12-12
- DOI
- https://doi.org/10.55730/1300-0144.6116
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00