Evaluation of Retinal Pigment Epithelium Melanin Using Polarization‐Sensitive OCT in Subthreshold Retinal Laser Therapy

The inverse correlation between individual visibility threshold laser power and RPE-PE, along with discrepancies in melanin density between the titration and macular regions, suggests that variations in RPE melanin density substantially influence the efficacy and safety of SMPL. These findings support the potential utility of PS-OCT-based RPE melanin assessment for optimizing SMPL parameters.

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Publication Details

Journal
Lasers in Surgery and Medicine
Published
2025-12-21
DOI
https://doi.org/10.1002/lsm.70089
Primary Topic
Optical Coherence Tomography Applications
Type
article
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OCT
article

Evaluation of Retinal Pigment Epithelium Melanin Using Polarization‐Sensitive OCT in Subthreshold Retinal Laser Therapy

Shuichiro Aoki, Ryo Terao, Keiko Azuma, Kohdai Kitamoto et al.
Lasers in Surgery and Medicine
Optical Coherence Tomography Applications
article

Evaluation of Retinal Pigment Epithelium Melanin Using Polarization‐Sensitive OCT in Subthreshold Retinal Laser Therapy

Shuichiro Aoki, Ryo Terao, Keiko Azuma, Kohdai Kitamoto, Yoko Miura
article en

Abstract

The inverse correlation between individual visibility threshold laser power and RPE-PE, along with discrepancies in melanin density between the titration and macular regions, suggests that variations in RPE melanin density substantially influence the efficacy and safety of SMPL. These findings support the potential utility of PS-OCT-based RPE melanin assessment for optimizing SMPL parameters.

Lasers in Surgery and MedicineVol. 58(2)
The University of Tokyo (JP), University of Lübeck (DE)
Openalex Percentile: Top 43%
Optical Coherence Tomography Applications
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