Influence of intrapatient variability in tacrolimus trough levels on acute rejection in pediatric kidney transplant recipients
In pediatric kidney transplant patients, the rejection risk was significantly associated with the magnitude of CV% rather than TTR. Special attention is warranted for therapeutic drug monitoring, especially beyond 3 months post-transplant, due to the increased risk of rejection compared to earlier stages post-transplantation.
Authors
- Mohamed A. Mobarez (ORCID: https://orcid.org/0000-0001-6148-7957)
- Samuel Makar (ORCID: https://orcid.org/0000-0001-9309-260X)
- E Abbas
- Fatina I. Fadel
- Mahmoud Ibrahim Mostafa
- Shorouk A. Othman
Institutions
- Cairo University (EG)
- Helwan University (EG)
Publication Details
- Journal
- Pediatric Nephrology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1007/s00467-025-07028-1
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cairo University