Tolerance of the venom immunotherapy switch from a highly purified aluminium hydroxide adsorbed hymenoptera venom extract to a nonpurified aqueous venom extract

In a real-world setting with product constraints, switching from purified AHA to a non-purified aqueous extract was feasible and generally well tolerated when dosing was individualised and monitored. Prospective, standardised studies with sting-challenge endpoints are warranted.