Beyond “futility thresholds”: An ethical framework for massive transfusion decisions

When limitations reflect capability gaps rather than patient physiology, institutions should treat these as sentinel events requiring structured review and potential systems improvement. This framework addresses the risk that unit-based thresholds become self-fulfilling limits or mask implicit rationing. By clarifying whether stopping reflects patient physiology or system constraints, it appropriately assigns accountability and enhances transparency in scarcity-driven decisions while maintaining rapid clinical judgment.

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Publication Details

Journal
Transfusion
Published
2025-12-22
DOI
https://doi.org/10.1111/trf.70048
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond “futility thresholds”: An ethical framework for massive transfusion decisions

Jay R. Malone
Transfusion
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

Beyond “futility thresholds”: An ethical framework for massive transfusion decisions

Jay R. Malone
article en

Abstract

When limitations reflect capability gaps rather than patient physiology, institutions should treat these as sentinel events requiring structured review and potential systems improvement. This framework addresses the risk that unit-based thresholds become self-fulfilling limits or mask implicit rationing. By clarifying whether stopping reflects patient physiology or system constraints, it appropriately assigns accountability and enhances transparency in scarcity-driven decisions while maintaining rapid clinical judgment.

Transfusion
Washington University in St. Louis (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 33%
Trauma, Hemostasis, Coagulopathy, Resuscitation
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