PTDSS1 serves as a prognostic biomarker of macrophage infiltration in pan-cancer and promotes hepatocellular carcinoma malignant phenotypes

PTDSS1 serves as a diagnostic and prognostic biomarker associated with macrophage infiltration, and may be a promising therapeutic target.

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Publication Details

Journal
Cancer Cell International
Published
2025-12-22
DOI
https://doi.org/10.1186/s12935-025-04144-8
Primary Topic
PI3K/AKT/mTOR signaling in cancer
Type
article
Field-Weighted Citation Impact
0.00

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article

PTDSS1 serves as a prognostic biomarker of macrophage infiltration in pan-cancer and promotes hepatocellular carcinoma malignant phenotypes

Xu Zhou, Yongguang Wei, Yu Chen, Zuyin Wan et al.
Cancer Cell International
PI3K/AKT/mTOR signaling in cancer
article

PTDSS1 serves as a prognostic biomarker of macrophage infiltration in pan-cancer and promotes hepatocellular carcinoma malignant phenotypes

Xu Zhou, Yongguang Wei, Yu Chen, Zuyin Wan, Chongjiu Qin, Haifei Qin, Haixiang Xie, Chenlu Lan, Zhongliu Wei, Guangzhi Zhu, Wei Qin, Tao Peng
article en

Abstract

PTDSS1 serves as a diagnostic and prognostic biomarker associated with macrophage infiltration, and may be a promising therapeutic target.

Cancer Cell InternationalVol. 25(1)
Guangxi University (CN), Guangxi Medical University (CN), The People's Hospital of Guangxi Zhuang Autonomous Region (CN), First Affiliated Hospital of GuangXi Medical University (CN), Tumor Hospital of Guangxi Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Guangxi Province, Division of Graduate Education
Good health and well-being
Openalex Percentile: Top 37%
PI3K/AKT/mTOR signaling in cancer
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PTDSS1 serves as a prognostic biomarker of macrophage infiltration in pan-cancer and promotes hepatocellular carcinoma malignant phenotypes — Xu Zhou, Yongguang Wei, et al. · Cancer Cell International (2025) | TGRS Research Map | TGRS