Prospective association between the gut microbiota and incident pneumonia: a cohort study of 6419 individuals
The gut microbiota composition, and especially the relative abundance of butyrate-producing bacteria, was associated with lower pneumonia risk in the population. These findings warrant further studies to investigate whether microbiome modulation to increase short chain fatty acid production through diet, prebiotics, or probiotics could reduce pneumonia risk.
Authors
- Anni Kauko (ORCID: https://orcid.org/0000-0003-1131-3865)
- Aki Samuli Havulinna (ORCID: https://orcid.org/0000-0002-4787-8959)
- Irina Wikki
- Leo Lahti
- Teemu Niiranen
- Joonatan Palmu
- Pekka Jousilahti
- Veikko Salomaa
- Rob Knight
Institutions
- University of Helsinki (FI)
- University of Turku (FI)
- Turku University Hospital (FI)
- University of California San Diego (US)
- Finnish Institute for Health and Welfare (FI)
- La Jolla Bioengineering Institute (US)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s12931-025-03453-w
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00