Effects of lactate administration on post-cardiac arrest myocardial dysfunction: an ex vivo study

Lactate administration did not improve post-CA myocardial function and was not deleterious. These findings suggest that the in vivo benefits of lactate administration are unlikely due to direct myocardial effects.

Authors

Neven Stevic
M. Cour
Delphine Baetz (ORCID: https://orcid.org/0000-0001-7678-062X)
René Ferrera (ORCID: https://orcid.org/0000-0001-7643-7784)
L. Argaud

Institutions

Université Claude Bernard Lyon 1 (FR)
Inserm (FR)
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
Hospices Civils de Lyon (FR)
Hôpital Edouard Herriot (FR)
Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition (FR)

Publication Details

Journal: Shock
Published: 2025-12-02
DOI: https://doi.org/10.1097/shk.0000000000002770
Primary Topic: Cardiac Arrest and Resuscitation
Type: article
Field-Weighted Citation Impact: 0.00

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article

Effects of lactate administration on post-cardiac arrest myocardial dysfunction: an ex vivo study

Neven Stevic, M. Cour, Delphine Baetz, René Ferrera et al.

Dec 2, 2025

Shock

Cardiac Arrest and Resuscitation

article

Effects of lactate administration on post-cardiac arrest myocardial dysfunction: an ex vivo study

Neven Stevic, M. Cour, Delphine Baetz, René Ferrera, L. Argaud

December 2, 2025article en

Abstract

Lactate administration did not improve post-CA myocardial function and was not deleterious. These findings suggest that the in vivo benefits of lactate administration are unlikely due to direct myocardial effects.

Shock

Université Claude Bernard Lyon 1 (FR), Inserm (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Hospices Civils de Lyon (FR), Hôpital Edouard Herriot (FR), Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition (FR)

Good health and well-being

Openalex Percentile: Top 27%

Cardiac Arrest and Resuscitation

DOI Source OpenAlex

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Effects of lactate administration on post-cardiac arrest myocardial dysfunction: an ex vivo study — Neven Stevic, M. Cour, et al. · Shock (2025) | TGRS Research Map | TGRS