Epigenome-wide mediation analysis identified Cytosine-phosphate-Guanine sites linking environmental factors with diabetes indicators

Four of the 8 CpGs (cg19693031, cg04816311, cg00574958, and cg11024682) were associated with the expression of genes implicated in diabetes and metabolism, including the <i>TXNIP</i>, <i>GPR146</i>, <i>CPT1A</i>, and <i>SREBF1</i> genes. These findings highlight the underlying epigenetic mechanism linking non-genetic factors with diabetes.

Authors

Institutions

Publication Details

Journal
Epigenomics
Published
2025-12-22
DOI
https://doi.org/10.1080/17501911.2025.2606041
Primary Topic
Genomics and Rare Diseases
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Epigenome-wide mediation analysis identified Cytosine-phosphate-Guanine sites linking environmental factors with diabetes indicators

Lin Wan-Yu
Epigenomics
Genomics and Rare Diseases
article

Epigenome-wide mediation analysis identified Cytosine-phosphate-Guanine sites linking environmental factors with diabetes indicators

Lin Wan-Yu
article en

Abstract

Four of the 8 CpGs (cg19693031, cg04816311, cg00574958, and cg11024682) were associated with the expression of genes implicated in diabetes and metabolism, including the <i>TXNIP</i>, <i>GPR146</i>, <i>CPT1A</i>, and <i>SREBF1</i> genes. These findings highlight the underlying epigenetic mechanism linking non-genetic factors with diabetes.

EpigenomicsVol. 18(1)
National Taiwan University (TW)
Openalex Percentile: Top 26%
Genomics and Rare Diseases
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Epigenome-wide mediation analysis identified Cytosine-phosphate-Guanine sites linking environmental factors with diabetes indicators — Lin Wan-Yu · Epigenomics (2025) | TGRS Research Map | TGRS