Efficacy, Safety and Tolerability of Lisdexamfetamine Dimesylate Treatment Compared With Placebo in Adults With Binge‐Eating Disorder: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

LDX demonstrates significant efficacy in reducing binge-eating behaviours and associated obsessive-compulsive symptoms in patients with BED, with a tolerable safety profile. These findings support the clinical use of LDX for managing BED.

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Publication Details

Journal
European Eating Disorders Review
Published
2025-12-21
DOI
https://doi.org/10.1002/erv.70070
Primary Topic
Eating Disorders and Behaviors
Type
article
Field-Weighted Citation Impact
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article

Efficacy, Safety and Tolerability of Lisdexamfetamine Dimesylate Treatment Compared With Placebo in Adults With Binge‐Eating Disorder: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Mateus Frizzo Messinger, Maurício Prätzel Ellwanger, Beatriz Westphalen Pomianoski, V. Astori et al.
European Eating Disorders Review
Eating Disorders and Behaviors
article

Efficacy, Safety and Tolerability of Lisdexamfetamine Dimesylate Treatment Compared With Placebo in Adults With Binge‐Eating Disorder: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Mateus Frizzo Messinger, Maurício Prätzel Ellwanger, Beatriz Westphalen Pomianoski, V. Astori, Manuela Pozza Ellwanger, Daniela Lopes Vieira
article en

Abstract

LDX demonstrates significant efficacy in reducing binge-eating behaviours and associated obsessive-compulsive symptoms in patients with BED, with a tolerable safety profile. These findings support the clinical use of LDX for managing BED.

European Eating Disorders Review
Universidade Federal de Minas Gerais (BR), Universidade Federal do Rio Grande do Sul (BR), Universidade Nove de Julho (BR), Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória (BR), Universidade do Contestado (BR)
Good health and well-being
Openalex Percentile: Top 28%
Eating Disorders and Behaviors
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