Statin therapy on dementia in elderly type 2 diabetes patients with delirium

Statin therapy, particularly at higher doses and intensities, is linked to reduced dementia risk and overall mortality in older T2DM patients with a history of delirium. These findings support the potential role of statins in the prevention of dementia in this high-risk population, warranting further investigation through randomized controlled trials.

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Publication Details

Journal
Diabetology & Metabolic Syndrome
Published
2025-12-22
DOI
https://doi.org/10.1186/s13098-025-02013-y
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Statin therapy on dementia in elderly type 2 diabetes patients with delirium

Mingyang Sun, Wu Szu-Yuan, Chen Wan-ming, Yitian Yang et al.
Diabetology & Metabolic Syndrome
Intensive Care Unit Cognitive Disorders
article

Statin therapy on dementia in elderly type 2 diabetes patients with delirium

Mingyang Sun, Wu Szu-Yuan, Chen Wan-ming, Yitian Yang, Mengrong Miao, Zhongyuan Lu, Xiaoling Wang, Jiaqiang Zhang, Shuang Lv
article en

Abstract

Statin therapy, particularly at higher doses and intensities, is linked to reduced dementia risk and overall mortality in older T2DM patients with a history of delirium. These findings support the potential role of statins in the prevention of dementia in this high-risk population, warranting further investigation through randomized controlled trials.

Diabetology & Metabolic SyndromeVol. 17(1)
Fu Jen Catholic University (TW), Asia University (TW), Luodong Poh-Ai Hospital (TW), Zhengzhou University (CN), Henan Academy of Sciences (CN), Henan Provincial People's Hospital (CN), Wan Fang Hospital (TW)
National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 33%
Intensive Care Unit Cognitive Disorders
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