Clinical characteristics of Graves’ disease following COVID-19 infection or vaccination: a multicenter case-control study

The clinical course was similar in all groups other than in some laboratory findings. Although the frequency of GO associated with COVID and VAC was lower, the proportion of cases with a Clinical Activity Score of ≥3 was higher compared to GD. This pattern suggests a potentially stronger immunologic trigger in these cases.

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Publication Details

Journal
TURKISH JOURNAL OF MEDICAL SCIENCES
Published
2025-12-12
DOI
https://doi.org/10.55730/1300-0144.6096
Primary Topic
SARS-CoV-2 and COVID-19 Research
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article
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article

Clinical characteristics of Graves’ disease following COVID-19 infection or vaccination: a multicenter case-control study

Asena Gökçay Canpolat, Kader Uğur, Bahri Evren, Yusuf Kayhan et al.
TURKISH JOURNAL OF MEDICAL SCIENCES
SARS-CoV-2 and COVID-19 Research
article

Clinical characteristics of Graves’ disease following COVID-19 infection or vaccination: a multicenter case-control study

Asena Gökçay Canpolat, Kader Uğur, Bahri Evren, Yusuf Kayhan, Hulya Iliksu Gozu, Kemal Ağbaht, Ziynet Alphan Üç, Mustafa Aydemir, Mustafa Cesur, Mehmet Ertürk, Adnan Batman, Oya Topaloğlu, Ayşe Kubat Üzüm, GÖKNUR YORULMAZ, Atilla Halil Elhan, Şefika Burçak Polat, Güven Bariş CANSU, Hayri Bostan, Reyhan Ersoy, Muhittin Yalcin, Alper Gürlek, Ümmü Mutlu, Ayşe Merve Ok, Bülent Okan Yildiz, Ayten Oğuz, DİLEK YAZICI, ERSEN KARAKILIÇ, ERMAN ÇAKAL, EMRE SERDAR SAYGILI, BANU KARA, FÜSUN BALOŞ TÖRÜNER, MERVE YILMAZ, SEVGÜL FAKI, SEÇKİN AKÇAY, NURCAN İNCE, CUNEYD ANIL, FARUK ALAGOL, MUSTAFA ŞAHİN, MURAT ERDOGAN FAİK, TÜLAY OMMA, TUGÇE ŞAH ÜNAL, BEKİR UCAN, MEHMET ÇAĞRI ÜNAL, BEKİR ÇAKIR, MEHMET AŞIK
article en

Abstract

The clinical course was similar in all groups other than in some laboratory findings. Although the frequency of GO associated with COVID and VAC was lower, the proportion of cases with a Clinical Activity Score of ≥3 was higher compared to GD. This pattern suggests a potentially stronger immunologic trigger in these cases.

TURKISH JOURNAL OF MEDICAL SCIENCESVol. 55(6)
Çanakkale Onsekiz Mart Üniversitesi (TR), Ministry of Health (TR), Koç University (TR), Ankara University (TR), University of Turku (FI), University of Health Science (KH), Dokuz Eylül University (TR), Akdeniz University (TR), Inonu University (TR), Usak University (TR), Ondokuz Mayıs University (TR), Haliç University (TR), Izmir Kâtip Çelebi University (TR), Kütahya Dumlupınar Üniversitesi (TR), Memorial Ankara Hospital (TR), Güven Hospital (TR), Samsun University (TR), Sağlık Bilimleri Üniversitesi (TR), Yüksek İhtisas Üniversitesi (TR), Lokman Hekim Üniversitesi (TR), İskenderun Technical University (TR), Kahramanmaraş Sütçü İmam University (TR), Eskişehir Osmangazi University (TR), Hacettepe University (TR), Istanbul University (TR), Marmara University (TR), University of Health Sciences Antigua (AG), Gazi University (TR)
Good health and well-being
Openalex Percentile: Top 32%
SARS-CoV-2 and COVID-19 Research
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