Spontaneous Suprachoroidal Hemorrhage in a Patient on Apixaban: A Case Report

Introduction We, herein, present a rare case report evaluating an elderly patient who developed spontaneous suprachoroidal hemorrhage (SSCH) while using apixaban (direct oral anticoagulant agent). Case Presentation An 82-year-old man with a known history of hypertension and atrial fibrillation on apixaban presented with a sudden onset of flashes, floaters, and a temporal curtain-like visual field defect in his right eye. He had no preceding history of trauma or recent ocular surgery. Ophthalmological examination revealed two large elevated grayish choroidal lesions with associated exudative retinal detachment. Ultrasonography and wide-field fluorescein angiography confirmed the diagnosis of SSCH. The patient was managed with topical steroids and cyclopentolate. One month later, the vision improved, and the hemorrhage showed signs of resolution. Discussion Direct oral anticoagulant agents (DOACs) are safer and carry a lower risk of major bleeding events compared to the traditionally used antiplatelet therapy and thrombolytic agents; however, patients may still be at risk of spontaneous suprachoroidal hemorrhage. Conclusion Spontaneous suprachoroidal hemorrhage can very rarely occur with the use of DOACs, with only two cases reported in the literature, and here, we present a case of SSCH in a patient while using apixaban.

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Publication Details

Journal
The Open Ophthalmology Journal
Published
2025-12-22
DOI
https://doi.org/10.2174/0118743641427164251008052645
Primary Topic
Child Abuse and Related Trauma
Type
article
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article

Spontaneous Suprachoroidal Hemorrhage in a Patient on Apixaban: A Case Report

Jinan Alhamad, Hend E. Alsafran
The Open Ophthalmology Journal
Child Abuse and Related Trauma
article

Spontaneous Suprachoroidal Hemorrhage in a Patient on Apixaban: A Case Report

Jinan Alhamad, Hend E. Alsafran
article en

Abstract

Introduction We, herein, present a rare case report evaluating an elderly patient who developed spontaneous suprachoroidal hemorrhage (SSCH) while using apixaban (direct oral anticoagulant agent). Case Presentation An 82-year-old man with a known history of hypertension and atrial fibrillation on apixaban presented with a sudden onset of flashes, floaters, and a temporal curtain-like visual field defect in his right eye. He had no preceding history of trauma or recent ocular surgery. Ophthalmological examination revealed two large elevated grayish choroidal lesions with associated exudative retinal detachment. Ultrasonography and wide-field fluorescein angiography confirmed the diagnosis of SSCH. The patient was managed with topical steroids and cyclopentolate. One month later, the vision improved, and the hemorrhage showed signs of resolution. Discussion Direct oral anticoagulant agents (DOACs) are safer and carry a lower risk of major bleeding events compared to the traditionally used antiplatelet therapy and thrombolytic agents; however, patients may still be at risk of spontaneous suprachoroidal hemorrhage. Conclusion Spontaneous suprachoroidal hemorrhage can very rarely occur with the use of DOACs, with only two cases reported in the literature, and here, we present a case of SSCH in a patient while using apixaban.

The Open Ophthalmology JournalVol. 20(1)
King Saud University (SA), King Khaled Eye Specialist Hospital (SA), Dhahran Health Center (SA)
Good health and well-being
Openalex Percentile: Top 18%
Child Abuse and Related Trauma
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