Inflammation, metabolic dysregulation, and depression profiles related to anhedonia and atypical, energy-related symptoms
Our results indicate consistent associations between several markers of inflammation and metabolic dysregulation with anhedonia and AES. Full characterization of depression profiles and their complex interrelations should be leveraged in future clinical research to select specific subgroup of depressed patients and develop more targeted treatment approaches.
Authors
- NJA van der Wee
- Y. Milaneschi
- J.C. Zwiep
- B.W.J.H. Penninx
- L. Nawijn
- F. Lamers
- C.H. Vinkers
Institutions
- Leiden University (NL)
- Leiden University Medical Center (NL)
- Amsterdam Neuroscience (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Brain Behavior and Immunity
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1016/j.bbi.2025.106240
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amsterdam University Medical Centers
- Universiteit Leiden
- Rijksuniversiteit Groningen
- ZonMw
- GGZ inGeest
- GGZ Friesland
- GGZ Drenthe
- Leids Universitair Medisch Centrum
- Universitair Medisch Centrum Groningen
- Hersenstichting
- Amsterdam Neuroscience