Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis Under Antifibrotic Therapy: A Retrospective Study

Lower %PEF and %TLC may predict poorer response to antifibrotics in IPF. These readily available PFT indices could serve as practical markers for risk stratification and early intervention. Prospective, multicenter studies are warranted to confirm predictive value.

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Publication Details

Journal
Cureus
Published
2025-12-22
DOI
https://doi.org/10.7759/cureus.99813
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis Under Antifibrotic Therapy: A Retrospective Study

Tomoo Kishaba, Hiroaki Nagano, Mariko Higa
Cureus
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Predictors of Disease Progression in Idiopathic Pulmonary Fibrosis Under Antifibrotic Therapy: A Retrospective Study

Tomoo Kishaba, Hiroaki Nagano, Mariko Higa
article en

Abstract

Lower %PEF and %TLC may predict poorer response to antifibrotics in IPF. These readily available PFT indices could serve as practical markers for risk stratification and early intervention. Prospective, multicenter studies are warranted to confirm predictive value.

CureusVol. 17(12)
Okinawa Prefectural Chubu Hospital (JP), Okinawa Prefecture (JP)
No poverty
Openalex Percentile: Top 29%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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