AMSTAR-PF: a critical appraisal tool for systematic reviews of prognostic factor studies
The ability to predict the onset or natural history of an illness, or how people may respond to a treatment, guides clinical decision making. These predictions are commonly based on prognostic factors: clinical, patient, or societal variables that are identified as being predictive of a certain future outcome. Prognostic factor research has increased across fields, with a subsequent increase in the number of systematic reviews of prognostic factors studies. Understanding the quality of such prognostic factor reviews is essential for confidence in their findings, but there is no quality appraisal instrument to specifically assess systematic reviews of prognostic factor studies. A MeaSurement Tool to Assess systematic Reviews of Prognostic Factor studies, AMSTAR-PF, has been developed to fill this gap.
Authors
- Lotty Hooft (ORCID: https://orcid.org/0000-0002-7950-2980)
- Sarah B. Wallwork (ORCID: https://orcid.org/0000-0003-1170-6263)
- Beverley Shea
- Nicole Skoetz (ORCID: https://orcid.org/0000-0003-4744-6192)
- Karel G. M. Moons (ORCID: https://orcid.org/0009-0004-7797-1056)
- Rebecca Riley
- G Lorimer Moseley
- Michael L Henry
- Johanna A A Damen
- Neil E O’Connell
Institutions
- University of Ottawa (CA)
- University of South Australia (AU)
- University of Cologne (DE)
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Bruyère (CA)
- University Hospital Cologne (DE)
- NIHR Birmingham Biomedical Research Centre (GB)
- Brunel University of London (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- BMJ
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1136/bmj-2025-085718
- Citations
- 1
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- University Hospitals Birmingham NHS Foundation Trust
- Australian Government
- National Institute for Health and Care Research
- Medical Research Council
- National Health and Medical Research Council
- Birmingham Biomedical Research Centre