Risk factors for developing acute kidney injury after heart transplant: A systematic review and meta-analysis

Age, BMI, diabetes, CKD, COPD, previous thoracic surgery, prolonged CPB time, extended mechanical ventilation, and ECMO use are significant predictors of AKI following heart transplantation, necessitating vigilant monitoring and individualized risk assessment. Conversely, factors such as LVAD implantation and inotrope use showed no significant association, highlighting the need for further investigation into their roles. Future prospective studies are essential to validate these findings, elucidate underlying mechanisms, and develop targeted interventions to mitigate AKI risk and improve patient outcomes.

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Publication Details

Journal
World Journal of Nephrology
Published
2025-12-22
DOI
https://doi.org/10.5527/wjn.v14.i4.110791
Citations
1
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
2.01
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article

Risk factors for developing acute kidney injury after heart transplant: A systematic review and meta-analysis

Mark Villanueva, Girish K. Mour, Mirza Muhammad Hadeed Khawar, Zainab Alvi et al.
1 citations
World Journal of Nephrology
Transplantation: Methods and Outcomes
2.01
article

Risk factors for developing acute kidney injury after heart transplant: A systematic review and meta-analysis

Mark Villanueva, Girish K. Mour, Mirza Muhammad Hadeed Khawar, Zainab Alvi, Ayesha Sehar, Muneeb Saifullah, Hamza Aka Khail, Hasnain Farooq, Obaid Ur Rehman, Manahil Shahzad, Muneeb Khawar, Sheraz Ali, Abdul Qadeer
article en
1 citations

Abstract

Age, BMI, diabetes, CKD, COPD, previous thoracic surgery, prolonged CPB time, extended mechanical ventilation, and ECMO use are significant predictors of AKI following heart transplantation, necessitating vigilant monitoring and individualized risk assessment. Conversely, factors such as LVAD implantation and inotrope use showed no significant association, highlighting the need for further investigation into their roles. Future prospective studies are essential to validate these findings, elucidate underlying mechanisms, and develop targeted interventions to mitigate AKI risk and improve patient outcomes.

World Journal of NephrologyVol. 14(4)
Services Institute of Medical Sciences (PK), King Edward Medical University (PK), Kabul University (AF), Mayo Clinic Hospital (US)
Openalex Percentile: Top 10%
Transplantation: Methods and Outcomes
2.01
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