Risk factors for developing acute kidney injury after heart transplant: A systematic review and meta-analysis
Age, BMI, diabetes, CKD, COPD, previous thoracic surgery, prolonged CPB time, extended mechanical ventilation, and ECMO use are significant predictors of AKI following heart transplantation, necessitating vigilant monitoring and individualized risk assessment. Conversely, factors such as LVAD implantation and inotrope use showed no significant association, highlighting the need for further investigation into their roles. Future prospective studies are essential to validate these findings, elucidate underlying mechanisms, and develop targeted interventions to mitigate AKI risk and improve patient outcomes.
Authors
- Mark Villanueva
- Girish K. Mour (ORCID: https://orcid.org/0000-0003-3764-0047)
- Mirza Muhammad Hadeed Khawar (ORCID: https://orcid.org/0009-0007-7371-4855)
- Zainab Alvi
- Ayesha Sehar
- Muneeb Saifullah (ORCID: https://orcid.org/0009-0003-8047-7270)
- Hamza Aka Khail
- Hasnain Farooq
- Obaid Ur Rehman
- Manahil Shahzad
- Muneeb Khawar
- Sheraz Ali
- Abdul Qadeer
Institutions
- Services Institute of Medical Sciences (PK)
- King Edward Medical University (PK)
- Kabul University (AF)
- Mayo Clinic Hospital (US)
Publication Details
- Journal
- World Journal of Nephrology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.5527/wjn.v14.i4.110791
- Citations
- 1
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.01