Regeneration of the pulp-dentin complex in mature teeth using autologous demineralized dentin matrix and dental pulp stem cells: two case reports
These cases suggest that autologous DPSCs combined with DDM can support dentin-like bridge formation and functional recovery in mature incisors, offering a potential biologically based alternative or adjunct to conventional root canal therapy for preserving structurally compromised teeth.
Authors
- Koichiro Iohara (ORCID: https://orcid.org/0000-0001-5563-6194)
- Misako Nakashima
- Hiroyuki Tanaka
- Noriaki Yoshihashi
Institutions
- Unitika (Japan) (JP)
- Air Water (Japan) (JP)
- Kishokai Medical Corporation (JP)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s12903-025-07578-8
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00