Successful re-administration after nano-liposomal irinotecan-induced severe hypersensitivity reaction: a case report
The novelty of this report lies in presenting, for the first time, the detailed course and process by which treatment was successfully continued in a patient experiencing severe HSR upon initial nal-IRI administration, through enhanced supportive care tailored to the characteristics of the drug and stepwise dose adjustment.
Authors
- Kazuaki Harada (ORCID: https://orcid.org/0000-0001-9577-1884)
- M Sugawara
- Ryota Kanno
- Yoshitaka Saito (ORCID: https://orcid.org/0000-0001-7159-8650)
- Yoshito Komatsu
- Yoh Takekuma
Institutions
- Hokkaido University of Science (JP)
- Hokkaido University Hospital (JP)
Publication Details
- Journal
- Journal of Pharmaceutical Health Care and Sciences
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s40780-025-00514-6
- Citations
- 1
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.39