Trichinella spiralis excretory-secretory proteins induced autophagy via activating AMPK/mTOR pathway and protected gut epithelial barrier
T. spiralis ESP-induced autophagy ultimately relieved and limited the damage of T. spiralis ESP to gut epithelial barrier, and ensured the T. spiralis survival and development in host gut mucosal epithelium.
Authors
- Ruo Dan Liu (ORCID: https://orcid.org/0000-0003-3451-9540)
- Xin Zhuo Zhang (ORCID: https://orcid.org/0009-0003-3576-8220)
- Zhong Quan Wang (ORCID: https://orcid.org/0000-0001-9376-9975)
- Pei Kun Cong
- Jin Yi Wu
- Jing Cui
- Ru Zhang
- Shao Rong Long
- Yao Zhang
Institutions
- Zhengzhou University (CN)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1371/journal.pntd.0013863
- Citations
- 1
- Primary Topic
- Parasitic Diseases Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.40