Phenome-Wide Associations of Polygenic Scores for Schizophrenia and Major Depression in 100,000 Chinese Adults

Our study suggests the context specificity of relationships between mental disorders and other traits, highlighting a potential role of sociocultural factors.

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Publication Details

Journal
Biological Psychiatry Global Open Science
Published
2025-12-22
DOI
https://doi.org/10.1016/j.bpsgos.2025.100681
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Phenome-Wide Associations of Polygenic Scores for Schizophrenia and Major Depression in 100,000 Chinese Adults

Daniel Avery, Andri Iona, Dan Schmidt-Valle, Hannah Fry et al.
Biological Psychiatry Global Open Science
Schizophrenia research and treatment
article

Phenome-Wide Associations of Polygenic Scores for Schizophrenia and Major Depression in 100,000 Chinese Adults

Daniel Avery, Andri Iona, Dan Schmidt-Valle, Hannah Fry, Iona Y. Millwood, Igor Pupko, Yiping Chen, Canqing Yu, Junshi Chen, Shixian Feng, Jun Lv, Huaidong Du, Zhengming Chen, Pei Pei, Sam Morris, Liming Li, Christiana Kartsonaki, Karoline Kuchenbaecker, Dianjianyi Sun, Baihan Wang, Ling Yang, Kuang Lin, Robin G. Walters, Derrick A. Bennett, Naomi R. Wray, Jonathan Clarke
article en

Abstract

Our study suggests the context specificity of relationships between mental disorders and other traits, highlighting a potential role of sociocultural factors.

Biological Psychiatry Global Open ScienceVol. 6(2)
The University of Queensland (AU), Peking University (CN), University of Oxford (GB), China National Center for Food Safety Risk Assessment (CN), Henan Provincial Center for Disease Control and Prevention (CN), University College London (GB)
Reduced inequalities
Openalex Percentile: Top 37%
Schizophrenia research and treatment
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