Laboratory Environments Mask Gait Differences Between Healthy Participants and Patients With Anterior Cruciate Ligament Reconstruction

Previous work suggests that people with mobility impairments move differently in the traditional gait laboratory than in natural environments, but the extent to which this possible divergence may have limited understanding of gait following anterior cruciate ligament reconstruction (ACLR) remains unknown. We hypothesized that 1) patients following ACLR walk more asymmetrically in daily life than in the laboratory and 2) differences between patients following ACLR and individuals with no gait pathologies would be more pronounced in daily life than in the laboratory. Twelve participants (six post-ACLR, six healthy) completed gait assessments in the laboratory with optical motion capture and inertial measurement units (IMUs) and in daily life with IMUs. Patients walked similarly to healthy participants in the laboratory, but in daily life they walked with a longer gait-cycle time ( $1.22~\pm ~0.03$ s vs. $1.08~\pm ~0.06$ s), longer double-support phase ( $21.8~\pm ~1.3$ % vs. $17.9~\pm ~2.7$ % Gait Cycle Time), and greater single-support asymmetry ( $8.4~\pm ~0.9$ % vs $4.1~\pm ~0.7$ %). While the reasons behind the observed differences were not studied, these results suggest that gait-analysis studies to date may have not realistically captured natural-environment behavior. Wearable sensors now offer a path toward deeper understanding of post-surgical gait and the specific patterns that may place certain patients at risk for post-traumatic osteoarthritis.

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Publication Details

Journal
IEEE Transactions on Neural Systems and Rehabilitation Engineering
Published
2025-12-22
DOI
https://doi.org/10.1109/tnsre.2025.3645799
Primary Topic
Balance, Gait, and Falls Prevention
Type
article
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article

Laboratory Environments Mask Gait Differences Between Healthy Participants and Patients With Anterior Cruciate Ligament Reconstruction

V.H. Giang Phan, Lauren R. Parola, Eni Halilaj
IEEE Transactions on Neural Systems and Rehabilitation Engineering
Balance, Gait, and Falls Prevention
article

Laboratory Environments Mask Gait Differences Between Healthy Participants and Patients With Anterior Cruciate Ligament Reconstruction

V.H. Giang Phan, Lauren R. Parola, Eni Halilaj
article en

Abstract

Previous work suggests that people with mobility impairments move differently in the traditional gait laboratory than in natural environments, but the extent to which this possible divergence may have limited understanding of gait following anterior cruciate ligament reconstruction (ACLR) remains unknown. We hypothesized that 1) patients following ACLR walk more asymmetrically in daily life than in the laboratory and 2) differences between patients following ACLR and individuals with no gait pathologies would be more pronounced in daily life than in the laboratory. Twelve participants (six post-ACLR, six healthy) completed gait assessments in the laboratory with optical motion capture and inertial measurement units (IMUs) and in daily life with IMUs. Patients walked similarly to healthy participants in the laboratory, but in daily life they walked with a longer gait-cycle time ( $1.22~\pm ~0.03$ s vs. $1.08~\pm ~0.06$ s), longer double-support phase ( $21.8~\pm ~1.3$ % vs. $17.9~\pm ~2.7$ % Gait Cycle Time), and greater single-support asymmetry ( $8.4~\pm ~0.9$ % vs $4.1~\pm ~0.7$ %). While the reasons behind the observed differences were not studied, these results suggest that gait-analysis studies to date may have not realistically captured natural-environment behavior. Wearable sensors now offer a path toward deeper understanding of post-surgical gait and the specific patterns that may place certain patients at risk for post-traumatic osteoarthritis.

IEEE Transactions on Neural Systems and Rehabilitation EngineeringVol. 34
Carnegie Mellon University (US)
Openalex Percentile: Top 25%
Balance, Gait, and Falls Prevention
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Laboratory Environments Mask Gait Differences Between Healthy Participants and Patients With Anterior Cruciate Ligament Reconstruction — V.H. Giang Phan, Lauren R. Parola, et al. · IEEE Transactions on Neural Systems and Rehabilitation Engineering (2025) | TGRS Research Map | TGRS