Lactylation-related lncRNAs can forecast prognosis and immune response of lung adenocarcinoma
This study developed an association between LRLs and outcomes in lung adenocarcinoma, suggesting that they can be used as a prognostic marker and therapeutic target. The observed differences in their expression between tumor and normal tissues further underline their significance in LUAD pathogenesis. By advancing the understanding of LUAD biology, this predictive model provides a novel platform for precision medicine, paving the way for personalized therapeutic strategies and improved prognostic accuracy for LUAD patients.
Authors
- Lan Zhang (ORCID: https://orcid.org/0000-0003-3675-1124)
- Bo Han (ORCID: https://orcid.org/0000-0002-4798-7725)
- Zhuowei Dong
- Ling Zhou (ORCID: https://orcid.org/0009-0008-8592-3870)
- Yinjiao Yuan
- Ruinian Zheng
- Yijing Shi
Institutions
- Anhui Medical University (CN)
- Dongguan People’s Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Third People's Hospital of Hefei (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1007/s12672-025-04306-0
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province