New insight into the risk stratification and treatment priority of breast cancer: TMT scoring system

The TMT score may represent a novel prognostic biomarker in breast cancer, highlighting the intricate relationship between mitochondrial transfer and tumor pathophysiology. Our findings suggested that targeting mitochondrial dynamics could be a potential therapeutic avenue for exploration, which might enhance breast cancer management strategies. Further exploration of the mitochondrial mechanisms in cancer biology may pave the way for more precise and effective therapeutic interventions.

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Publication Details

Journal
International Journal of Surgery
Published
2025-12-22
DOI
https://doi.org/10.1097/js9.0000000000004615
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

New insight into the risk stratification and treatment priority of breast cancer: TMT scoring system

Zhe Qi, Liangdong Li, Yuechao Yang, Xiaojun Wu et al.
International Journal of Surgery
Ferroptosis and cancer prognosis
article

New insight into the risk stratification and treatment priority of breast cancer: TMT scoring system

Zhe Qi, Liangdong Li, Yuechao Yang, Xiaojun Wu, C. Zhou, Zhisu Wang, Ya Cao, Y-T Gao, Xin Chen, Mingtao Feng, Lei Chen, Bin Hao, Deheng Li, Sen Li
article en

Abstract

The TMT score may represent a novel prognostic biomarker in breast cancer, highlighting the intricate relationship between mitochondrial transfer and tumor pathophysiology. Our findings suggested that targeting mitochondrial dynamics could be a potential therapeutic avenue for exploration, which might enhance breast cancer management strategies. Further exploration of the mitochondrial mechanisms in cancer biology may pave the way for more precise and effective therapeutic interventions.

International Journal of Surgery
Shanghai Medical College of Fudan University (CN), Fudan University Shanghai Cancer Center (CN)
Good health and well-being
Openalex Percentile: Top 29%
Ferroptosis and cancer prognosis
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