Peri-Prostatic Pacinian Corpuscles: A Multi-Institutional Series

The finding of Pacinian corpuscles (PCs) in association with the prostate gland is an anatomical rarity. We present the largest series to date of 23 peri-prostatic PCs from 14 patients identified during routine reporting of radical prostatectomy and cystoprostatectomy specimens with or without pelvic lymph node dissection. The clinicopathological features of this perplexing anatomical structure, including the location, size, shape, immunohistochemical and ultrastuctural findings are thoroughly investigated. We also identify for the first time the clustered appearance of PCs in 2 patients consistent with PC hyperplasia.

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Publication Details

Journal
International Journal of Surgical Pathology
Published
2025-12-22
DOI
https://doi.org/10.1177/10668969251405427
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Peri-Prostatic Pacinian Corpuscles: A Multi-Institutional Series

Lisa S. Friedman, Laurence A. Galea, Sree Appu, Benjamin Frank Goeppert et al.
International Journal of Surgical Pathology
Prostate Cancer Diagnosis and Treatment
article

Peri-Prostatic Pacinian Corpuscles: A Multi-Institutional Series

Lisa S. Friedman, Laurence A. Galea, Sree Appu, Benjamin Frank Goeppert, Miruna Claudia Popescu, Mahmut Akgul, Ankur R Sangoi
article en

Abstract

The finding of Pacinian corpuscles (PCs) in association with the prostate gland is an anatomical rarity. We present the largest series to date of 23 peri-prostatic PCs from 14 patients identified during routine reporting of radical prostatectomy and cystoprostatectomy specimens with or without pelvic lymph node dissection. The clinicopathological features of this perplexing anatomical structure, including the location, size, shape, immunohistochemical and ultrastuctural findings are thoroughly investigated. We also identify for the first time the clustered appearance of PCs in 2 patients consistent with PC hyperplasia.

International Journal of Surgical Pathology
Brigham and Women's Hospital (US), Harvard University (US), Ludwigsburg University of Education (DE), Cabrini Hospital (AU), Sonic Healthcare (Germany) (DE), Klinikum Ludwigsburg (DE), Stanford University (US)
Openalex Percentile: Top 29%
Prostate Cancer Diagnosis and Treatment
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Peri-Prostatic Pacinian Corpuscles: A Multi-Institutional Series — Lisa S. Friedman, Laurence A. Galea, et al. · International Journal of Surgical Pathology (2025) | TGRS Research Map | TGRS