Preclinical characterization of 3p-C-DEPA-NCS and 3p-C-DEPA-TFP-PEG4 as potential Actinium-225 bifunctional chelators using DOTA-NCS and macropa-NCS as benchmarks

Authors

Siphelele Siphesihle Pearl Malaza (ORCID: https://orcid.org/0000-0002-7533-1491)
Thomas Cardinaels (ORCID: https://orcid.org/0000-0002-2695-1002)
Jessica Pougoue Ketchemen (ORCID: https://orcid.org/0000-0002-4574-8720)
Emmanuel Nwangele (ORCID: https://orcid.org/0000-0002-4269-822X)
Simon Leekens (ORCID: https://orcid.org/0000-0002-1678-698X)
Humphrey Fonge (ORCID: https://orcid.org/0000-0001-9388-6872)
Stephen Ahenkorah (ORCID: https://orcid.org/0000-0002-3632-829X)
Maarten Ooms
Frederik Cleeren

Institutions

University of Saskatchewan (CA)
Belgian Nuclear Research Centre (BE)
Hôtel-Dieu de Québec (CA)
University of Iowa Health Care (US)
Université Laval (CA)
KU Leuven (BE)

Publication Details

Journal: EJNMMI Radiopharmacy and Chemistry
Published: 2025-12-22
DOI: https://doi.org/10.1186/s41181-025-00408-w
Citations: 1
Primary Topic: Radiopharmaceutical Chemistry and Applications
Type: article
Field-Weighted Citation Impact: 1.36

Funders

KU Leuven
Canadian Institutes of Health Research

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article

Preclinical characterization of 3p-C-DEPA-NCS and 3p-C-DEPA-TFP-PEG4 as potential Actinium-225 bifunctional chelators using DOTA-NCS and macropa-NCS as benchmarks

Siphelele Siphesihle Pearl Malaza, Thomas Cardinaels, Jessica Pougoue Ketchemen, Emmanuel Nwangele et al.

Dec 22, 2025

1 citations

EJNMMI Radiopharmacy and Chemistry

Radiopharmaceutical Chemistry and Applications

1.36

article

Preclinical characterization of 3p-C-DEPA-NCS and 3p-C-DEPA-TFP-PEG4 as potential Actinium-225 bifunctional chelators using DOTA-NCS and macropa-NCS as benchmarks

Siphelele Siphesihle Pearl Malaza, Thomas Cardinaels, Jessica Pougoue Ketchemen, Emmanuel Nwangele, Simon Leekens, Humphrey Fonge, Stephen Ahenkorah, Maarten Ooms, Frederik Cleeren

December 22, 2025article en

1 citations

Abstract

No abstract available for this paper.

EJNMMI Radiopharmacy and ChemistryVol. 10(1)

University of Saskatchewan (CA), Belgian Nuclear Research Centre (BE), Hôtel-Dieu de Québec (CA), University of Iowa Health Care (US), Université Laval (CA), KU Leuven (BE)

KU Leuven, Canadian Institutes of Health Research

Affordable and clean energy

Openalex Percentile: Top 13%

Radiopharmaceutical Chemistry and Applications

1.36

DOI Open Access PDF OpenAlex

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Preclinical characterization of 3p-C-DEPA-NCS and 3p-C-DEPA-TFP-PEG4 as potential Actinium-225 bifunctional chelators using DOTA-NCS and macropa-NCS as benchmarks — Siphelele Siphesihle Pearl Malaza, Thomas Cardinaels, et al. · EJNMMI Radiopharmacy and Chemistry (2025) | TGRS Research Map | TGRS