Advantages of Customized Titanium Meshes in Oral Bone Regeneration: A Literature Review and Two Cases Presentation Using Customized Meshes

Bone grafting before dental implants are placed is one of the most common procedures nowadays in dentistry. The reality is that CBCT and also CAD-CAM technology have changed all what has to be related to it. Customized titanium meshes (CTMs) have become a reliable option for guided bone regeneration (GBR), allowing precise anatomical reconstruction of alveolar defects through CAD/CAM technology. Their rigidity, biocompatibility, and design flexibility provide superior mechanical stability and soft-tissue management compared with conventional collagen membranes or PTR membranes. This review analyzes the biological, technical, and clinical advantages of CTMs, summarizing current evidence on their predictability, technical considerations, and limitations. Additionally, it explores the role of digital planning and 3D printing in optimizing surgical outcomes, minimizing intraoperative adjustments, and improving patient-specific adaptation. CTMs have demonstrated high success rates in maintaining space for bone regeneration, reducing complications such as mesh exposure, and achieving satisfactory aesthetic and functional results. The review also discusses potential complications, handling protocols, and long-term clinical follow-up. Furthermore, it presents two cases in which Element® Customized Ti-Meshes were used, showing excellent integration and bone volume stability. After successful osteointegration of the bone graft, dental implants were placed, achieving predictable and stable restorative outcomes.