Gut microbiota-derived trimethylamine N-oxide exacerbates diabetic nephropathy by promoting renal fibrosis
DN is associated with gut microbiota alterations that potentiate TMAO generation, contributing to renal injury and fibrotic progression. While TMAO's role in fibrosis warrants further validation, these findings implicate the gut-kidney axis in DN pathogenesis.
Authors
- Yuejuan Song
- Qiangsheng Feng (ORCID: https://orcid.org/0000-0003-0096-5462)
- Fei-Fei Ma
- Bang Xing
- Bo Yang
- Xiao-Qin Ha
- Xi-Liang Bin
Institutions
- People's Liberation Army 401 Hospital (CN)
- Army Sustainment University (US)
Publication Details
- Journal
- World Journal of Nephrology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.5527/wjn.v14.i4.112066
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81