Efficacy and safety of tranilast combined with minocycline in the treatment of moderate-to-severe rosacea: a prospective, randomized controlled study

In our study, patients with moderate to severe rosacea treated with tranilast showed a favorable clinical response and experienced no serious adverse events. The combination therapy yielded better outcomes than minocycline monotherapy, especially in improving facial erythema.

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Publication Details

Journal
Journal of Dermatological Treatment
Published
2025-12-22
DOI
https://doi.org/10.1080/09546634.2025.2597711
Primary Topic
Acne and Rosacea Treatments and Effects
Type
article
Field-Weighted Citation Impact
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article

Efficacy and safety of tranilast combined with minocycline in the treatment of moderate-to-severe rosacea: a prospective, randomized controlled study

Hongshan Liu, Yale Liu, Jingchen Liang, Shujuan He et al.
Journal of Dermatological Treatment
Acne and Rosacea Treatments and Effects
article

Efficacy and safety of tranilast combined with minocycline in the treatment of moderate-to-severe rosacea: a prospective, randomized controlled study

Hongshan Liu, Yale Liu, Jingchen Liang, Shujuan He, Weihui Zeng, Ying Chen, Zhao Wang, Mengyao Yang
article en

Abstract

In our study, patients with moderate to severe rosacea treated with tranilast showed a favorable clinical response and experienced no serious adverse events. The combination therapy yielded better outcomes than minocycline monotherapy, especially in improving facial erythema.

Journal of Dermatological TreatmentVol. 37(1)
Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Good health and well-being
Openalex Percentile: Top 25%
Acne and Rosacea Treatments and Effects
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