Prognostic Performance of Phosphatidylethanol With Noninvasive Liver Fibrosis Tests in Alcohol-Related Liver Disease

PEth predicts hepatic decompensation independently of fibrosis-based NITs in individuals at risk of ALD. Although its prognostic performance declines rapidly, repeated PEth measurements maintain prognostic discrimination.

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Publication Details

Journal
Gastroenterology
Published
2025-12-22
DOI
https://doi.org/10.1053/j.gastro.2025.10.005
Primary Topic
Alcohol Consumption and Health Effects
Type
article
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article

Prognostic Performance of Phosphatidylethanol With Noninvasive Liver Fibrosis Tests in Alcohol-Related Liver Disease

Katrine Holtz Thorhauge, Peter Andersen, Melanie Bergmann, K. Bech et al.
Gastroenterology
Alcohol Consumption and Health Effects
article

Prognostic Performance of Phosphatidylethanol With Noninvasive Liver Fibrosis Tests in Alcohol-Related Liver Disease

Katrine Holtz Thorhauge, Peter Andersen, Melanie Bergmann, K. Bech, Katrine Prier Lindvig, Eric Petersen, Mads Israelsen, Ida Falk Villesen, Stine Johansen, Johanne Kragh Hansen, Nikolaj Torp, M.A. Karsdal, Maja Thiele, Georg Semmler, C. Rønn Hansen, Helle Lindholm Schnefeld, Mette Lehmann Andersen, Markus Maagaard, Aleksander Krag, Ellen Lyngbeck Jensen, Diana Julie Leeming
article en

Abstract

PEth predicts hepatic decompensation independently of fibrosis-based NITs in individuals at risk of ALD. Although its prognostic performance declines rapidly, repeated PEth measurements maintain prognostic discrimination.

GastroenterologyVol. 170(4)
University of Southern Denmark (DK), Odense University Hospital (DK), Herlev Hospital (DK), World Health Organization - Denmark (DK), Lillebaelt Hospital (DK), Nordic Bioscience (Denmark) (DK)
Reduced inequalities, Peace, Justice and strong institutions
Openalex Percentile: Top 31%
Alcohol Consumption and Health Effects
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