An unsupervised tool for biomarker discovery and cancer subtyping applied to glioblastoma

TRIM-IT provides a novel approach for analyzing high-dimensional omics data while preserving key biological insights. Its ability to identify meaningful patient subgroups and molecular signatures highlights its applicability across various biomedical research contexts. The tool is implemented in R and the code is publicly available for reproduction and adaptation to other studies.

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Publication Details

Journal
BioData Mining
Published
2025-12-22
DOI
https://doi.org/10.1186/s13040-025-00500-6
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

An unsupervised tool for biomarker discovery and cancer subtyping applied to glioblastoma

Marcos Raydan, Marta Lopes, Roberta Coletti, J. Orestes Cerdeira
BioData Mining
Glioma Diagnosis and Treatment
article

An unsupervised tool for biomarker discovery and cancer subtyping applied to glioblastoma

Marcos Raydan, Marta Lopes, Roberta Coletti, J. Orestes Cerdeira
article en

Abstract

TRIM-IT provides a novel approach for analyzing high-dimensional omics data while preserving key biological insights. Its ability to identify meaningful patient subgroups and molecular signatures highlights its applicability across various biomedical research contexts. The tool is implemented in R and the code is publicly available for reproduction and adaptation to other studies.

BioData MiningVol. 18(1)
Universidade Nova de Lisboa (PT)
UNIDEMI, Fundação para a Ciência e a Tecnologia
Openalex Percentile: Top 27%
Glioma Diagnosis and Treatment
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