Mitigating nickel-induced toxicity: the protective role of native probiotic strains on oxidative stress and inflammatory pathways in mice lung tissues

This research highlights the harmful impact of Nickel, a heavy metal, on lung health, while simultaneously examining the beneficial properties of probiotics, particularly their antioxidant and anti-inflammatory effects. Given the significant risk associated with heavy metal exposure, the incorporation of probiotics emerges as a promising strategy to mitigate oxidative stress and prevent a range of pulmonary disorders, including those linked to inflammation.

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Publication Details

Journal
BMC Pharmacology and Toxicology
Published
2025-12-22
DOI
https://doi.org/10.1186/s40360-025-01047-2
Primary Topic
Heavy Metal Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
0.00

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article

Mitigating nickel-induced toxicity: the protective role of native probiotic strains on oxidative stress and inflammatory pathways in mice lung tissues

Fatemeh Haririzadeh Jouriani, Elham Haj Agha Gholizadeh Khiavi, Mahdi Rohani, Shadi Aghamohammad et al.
BMC Pharmacology and Toxicology
Heavy Metal Exposure and Toxicity
article

Mitigating nickel-induced toxicity: the protective role of native probiotic strains on oxidative stress and inflammatory pathways in mice lung tissues

Fatemeh Haririzadeh Jouriani, Elham Haj Agha Gholizadeh Khiavi, Mahdi Rohani, Shadi Aghamohammad, Niloofar Rezaie, Shokufeh Beglari
article en

Abstract

This research highlights the harmful impact of Nickel, a heavy metal, on lung health, while simultaneously examining the beneficial properties of probiotics, particularly their antioxidant and anti-inflammatory effects. Given the significant risk associated with heavy metal exposure, the incorporation of probiotics emerges as a promising strategy to mitigate oxidative stress and prevent a range of pulmonary disorders, including those linked to inflammation.

BMC Pharmacology and ToxicologyVol. 26(1)
Pasteur Institute of Iran (IR), Islamic Azad University, Science and Research Branch (IR)
Islamic Azad University, University of Tehran, Pasteur Institute of Iran
Good health and well-being
Openalex Percentile: Top 34%
Heavy Metal Exposure and Toxicity
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