Intense 68Ga-PSMA-11 Uptake of Perihilar Cholangiocarcinoma

An immunohistochemical study demonstrates that most of the cholangiocarcinomas have PSMA expression in the tumor neovasculature. PSMA PET findings of cholangiocarcinomas are rarely reported. We describe 68 Ga-PSMA-11 PET/CT and delayed abdominal 68 Ga-PSMA-11 PET/MRI findings in a case of mass-forming type of perihilar cholangiocarcinoma. The tumor showed intense PSMA uptake with SUV max of 10.8 on 68 Ga-PSMA-11 PET/CT and SUV max of 7.8 on delayed 68 Ga-PSMA-11 PET/MRI.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-12-22
DOI
https://doi.org/10.1097/rlu.0000000000006107
Primary Topic
Prostate Cancer Treatment and Research
Type
article
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article

Intense 68Ga-PSMA-11 Uptake of Perihilar Cholangiocarcinoma

Xiandong Song, Xiaojun Man, Changming Dong, Aisheng Dong
Clinical Nuclear Medicine
Prostate Cancer Treatment and Research
article

Intense 68Ga-PSMA-11 Uptake of Perihilar Cholangiocarcinoma

Xiandong Song, Xiaojun Man, Changming Dong, Aisheng Dong
article en

Abstract

An immunohistochemical study demonstrates that most of the cholangiocarcinomas have PSMA expression in the tumor neovasculature. PSMA PET findings of cholangiocarcinomas are rarely reported. We describe 68 Ga-PSMA-11 PET/CT and delayed abdominal 68 Ga-PSMA-11 PET/MRI findings in a case of mass-forming type of perihilar cholangiocarcinoma. The tumor showed intense PSMA uptake with SUV max of 10.8 on 68 Ga-PSMA-11 PET/CT and SUV max of 7.8 on delayed 68 Ga-PSMA-11 PET/MRI.

Clinical Nuclear MedicineVol. 51(2)
Qingdao University (CN), Second Military Medical University (CN), Yuhuangding Hospital (CN), Changhai Hospital (CN), Shenyang Fifth People Hospital (CN), First Hospital of China Medical University (CN), China Medical University (CN)
Good health and well-being
Openalex Percentile: Top 29%
Prostate Cancer Treatment and Research
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