Rapid and selective gut microbiome modulation by polyherbal formulation in type 2 diabetes
Short-term polyherbal formulation co-administration significantly modulates gut microbiota, promoting beneficial taxa, such as Bifidobacterium in metformin-treated type 2 diabetes patients. This supports the potential role of the polyherbal formulation in microbiome-targeted strategies to improve metformin tolerability and effectiveness.
Authors
- Somit Kumar (ORCID: https://orcid.org/0000-0001-8897-1976)
- Uģis Klētnieks
- Jānis Plūme (ORCID: https://orcid.org/0000-0002-0761-4334)
- Kakarla Sai Mitravinda
- Svjatoslavs Kistkins (ORCID: https://orcid.org/0000-0002-6463-0664)
- Valdis Pīrāgs (ORCID: https://orcid.org/0000-0002-3650-7394)
- Monta Brīvība
- Harijs Saušs
- Jana Baranova
- Jānis Kloviņš
- Sintija Sauša
- Tatjana Kozlova
- Annija Zodāne
Institutions
- Latvian Biomedical Research and Study Centre (LV)
- Riga Technical University (LV)
- Baltic International Academy (LV)
- Pauls Stradiņš Clinical University Hospital (LV)
- Baltic Studies Centre (LV)
- University of Latvia (LV)
Publication Details
- Journal
- Endocrine Connections
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1530/ec-25-0463
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00