The quadruple helix and the role of HEIs as innovation brokers in disadvantaged areas

This conceptual paper explores the drivers and barriers of university–business collaboration in disadvantaged areas, emphasising its potential to foster inclusive local development. Starting from a review of the academic and policy literature, it proposes a framework that situates higher education institutions as innovation brokers, crucial actors in building trust, facilitating coordination and translating knowledge across quadruple helix stakeholders. The study underscores the need for place-based strategies and multi-stakeholder coalitions to address complex challenges and support co-creation in regional innovation ecosystems.