Dysregulation of iron metabolism in preeclamptic women with small-for-gestational-age offspring: A retrospective cohort analysis with nested case-control assessment

Preeclampsia is associated with disrupted iron balance, characterized by maternal iron overload and relative fetal iron insufficiency due to placental dysregulation. The findings support the sub - classification of preeclampsia into placental (PE + SGA) and maternal (PE - SGA) subtypes. This cautions against universal iron supplementation and highlights the need for personalized management.