Degradation of Elastic Fiber Triggers Lacrimal Gland Dysfunction in Marfan Syndrome Mice
Abnormalities of elastic fibers in LG ECM due to fibrillin-1 deficiency can lead to inflammatory and fibrotic disorders and ultimately LG dysfunction.
Authors
- Xinyu Zhang (ORCID: https://orcid.org/0000-0002-9774-7092)
- Ge Jin (ORCID: https://orcid.org/0000-0002-8517-7969)
- Xinxin Liu (ORCID: https://orcid.org/0009-0002-7525-3400)
- Lu Hu
- Liyan Liu (ORCID: https://orcid.org/0000-0002-4931-6917)
- Danying Zheng
- Qian Ye (ORCID: https://orcid.org/0009-0003-7776-9731)
- Lingyi Liang
- Bing Xiao
- Charlotte Young
Institutions
- Sun Yat-sen University (CN)
- Albany Medical Center Hospital (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1167/iovs.66.15.63
- Primary Topic
- Connective tissue disorders research
- Type
- article
- Field-Weighted Citation Impact
- 0.00