Successful discontinuation of levothyroxine in a known case of hypothyroidism through personalised homoeopathic treatment: An evidence-based case report

Hypothyroidism is a common endocrine disorder caused by thyroid hormone deficiency, primarily affecting women and older individuals, with symptoms such as fatigue, weight gain, cold intolerance, and dry skin. A 23-year-old woman presented with progressive weight gain over six months and hair loss for one year. Despite being on levothyroxine 50 mcg for a year, her symptoms persisted and worsened, leading her to discontinue hormone replacement therapy and seek alternative management. Initial thyroid function tests showed elevated thyroid-stimulating hormone (TSH) levels (6.7 µIU/ml), confirming hypothyroidism. She was transitioned to a personalized homoeopathic treatment plan while levothyroxine was gradually tapered, along with dietary modifications that excluded goitrogenic foods such as soy products, cruciferous vegetables, and millet. During tapering, TSH levels transiently increased to 27.9 µIU/ml but later normalized to 3.72 µIU/ml with continued homoeopathic management. The patient reported significant improvement in symptoms, including reduction in hair fall and weight loss from 70.8 kg to 61.2 kg. Causal attribution of the clinical outcome was assessed using the Modified Naranjo Criteria. This case highlights the potential role of individualized homoeopathic treatment in managing hypothyroidism and minimizing dependency on conventional hormone therapy, warranting further systematic research.