Prostatic Abscess Due to Dual Infection With Mycobacterium tuberculosis and Stenotrophomonas maltophilia

Prostatic abscess as an isolated entity is an infrequent and extremely rare manifestation of genitourinary tuberculosis. We report a case of a middle-aged male with type 2 diabetes mellitus and hypertension who presented with persistent lower urinary tract symptoms and fever. Imaging revealed a multiloculated prostatic abscess. Pus culture grew <i>Stenotrophomonas maltophilia</i>, while a cartridge-based nucleic acid amplification test confirmed <i>Mycobacterium tuberculosis</i>. The patient was managed with appropriate antimicrobial therapy, antitubercular treatment, and supportive care, leading to complete resolution of the abscess. This case underscores the diagnostic challenge posed by dual-pathogen prostatic abscesses and emphasizes the need to consider a tuberculous etiology even in the absence of pulmonary involvement, especially in endemic regions.