TELO2 mediates parabens-induced breast carcinogenesis: a comprehensive network analysis
Our integrative findings suggest that parabens may exert deleterious effects in the context of breast cancer by specifically targeting the TELO2 gene and its associated regulatory networks and pathways. These findings not only advance our understanding of the environmental drivers of BC but also pave the way for future research aimed at mitigating the disease's health burden through targeted interventions against harmful environmental exposures.
Authors
- Huaixi Xing (ORCID: https://orcid.org/0000-0002-5210-013X)
- Zhulin Bu
- Yuting Li
- Yuting Dai
- Lin Yang
- Jing Ren
- Xiaofen Li
- Xianglong Meng
- Yuhui Wu
- Shuosheng Zhang
- Bin Dong
Institutions
- Beijing University of Chinese Medicine (CN)
- Jinzhong University (CN)
- Shanxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s40360-025-01072-1
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 0.00