TELO2 mediates parabens-induced breast carcinogenesis: a comprehensive network analysis

Our integrative findings suggest that parabens may exert deleterious effects in the context of breast cancer by specifically targeting the TELO2 gene and its associated regulatory networks and pathways. These findings not only advance our understanding of the environmental drivers of BC but also pave the way for future research aimed at mitigating the disease's health burden through targeted interventions against harmful environmental exposures.

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Publication Details

Journal
BMC Pharmacology and Toxicology
Published
2025-12-22
DOI
https://doi.org/10.1186/s40360-025-01072-1
Primary Topic
Effects and risks of endocrine disrupting chemicals
Type
article
Field-Weighted Citation Impact
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article

TELO2 mediates parabens-induced breast carcinogenesis: a comprehensive network analysis

Huaixi Xing, Zhulin Bu, Yuting Li, Yuting Dai et al.
BMC Pharmacology and Toxicology
Effects and risks of endocrine disrupting chemicals
article

TELO2 mediates parabens-induced breast carcinogenesis: a comprehensive network analysis

Huaixi Xing, Zhulin Bu, Yuting Li, Yuting Dai, Lin Yang, Jing Ren, Xiaofen Li, Xianglong Meng, Yuhui Wu, Shuosheng Zhang, Bin Dong
article en

Abstract

Our integrative findings suggest that parabens may exert deleterious effects in the context of breast cancer by specifically targeting the TELO2 gene and its associated regulatory networks and pathways. These findings not only advance our understanding of the environmental drivers of BC but also pave the way for future research aimed at mitigating the disease's health burden through targeted interventions against harmful environmental exposures.

BMC Pharmacology and ToxicologyVol. 27(1)
Beijing University of Chinese Medicine (CN), Jinzhong University (CN), Shanxi University of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 34%
Effects and risks of endocrine disrupting chemicals
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