Association of endocrine autoantibodies (anti-TPO, anti-GAD, anti-insulin) with histopathological severity in pediatric Celiac disease: a retrospective cohort study

Our study demonstrated that the presence of autoantibodies associated with T1DM and ATD was correlated with more severe histopathological findings in patients with CD. There is a need for prospective studies investigating the role of these autoantibodies in predicting the prognosis of CD.

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Publication Details

Journal
BMC Pediatrics
Published
2025-12-22
DOI
https://doi.org/10.1186/s12887-025-06471-1
Primary Topic
Celiac Disease Research and Management
Type
article
Field-Weighted Citation Impact
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article

Association of endocrine autoantibodies (anti-TPO, anti-GAD, anti-insulin) with histopathological severity in pediatric Celiac disease: a retrospective cohort study

Aybike Koç, Hatice Kup, Merve Usta, Büşra Tetik Dinçer et al.
BMC Pediatrics
Celiac Disease Research and Management
article

Association of endocrine autoantibodies (anti-TPO, anti-GAD, anti-insulin) with histopathological severity in pediatric Celiac disease: a retrospective cohort study

Aybike Koç, Hatice Kup, Merve Usta, Büşra Tetik Dinçer, Nafiye Urgancı
article en

Abstract

Our study demonstrated that the presence of autoantibodies associated with T1DM and ATD was correlated with more severe histopathological findings in patients with CD. There is a need for prospective studies investigating the role of these autoantibodies in predicting the prognosis of CD.

BMC PediatricsVol. 26(1)
Memorial Ankara Hospital (TR), Sağlık Bilimleri Üniversitesi (TR), Şişli Etfal Eğitim ve Araştırma Hastanesi (TR), University of Health Sciences Antigua (AG)
Good health and well-being
Openalex Percentile: Top 28%
Celiac Disease Research and Management
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