Weighing Dose‐Related Benefits and Risks of Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus

For patients with SLE, higher-dose HCQ improves effectiveness, with reduced risks of CAD and VTE. There was no dose-related difference in the risk of HCQ retinopathy for patients with SLE aged younger than 45 years. Our study emphasizes the need for weighing the benefits and risks of optimal HCQ dosage in managing SLE.

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Publication Details

Journal
Arthritis & Rheumatology
Published
2025-12-22
DOI
https://doi.org/10.1002/art.70022
Citations
1
Primary Topic
Drug-Induced Ocular Toxicity
Type
article
Field-Weighted Citation Impact
1.71
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article

Weighing Dose‐Related Benefits and Risks of Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus

Edward Chia‐Cheng Lai, Brian Meng‐Hsun Li, Meng‐Yu Weng, Swu‐Jane Lin et al.
1 citations
Arthritis & Rheumatology
Drug-Induced Ocular Toxicity
1.71
article

Weighing Dose‐Related Benefits and Risks of Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus

Edward Chia‐Cheng Lai, Brian Meng‐Hsun Li, Meng‐Yu Weng, Swu‐Jane Lin, Jia‐Horung Hung, Po‐Cheng Yang
article en
1 citations

Abstract

For patients with SLE, higher-dose HCQ improves effectiveness, with reduced risks of CAD and VTE. There was no dose-related difference in the risk of HCQ retinopathy for patients with SLE aged younger than 45 years. Our study emphasizes the need for weighing the benefits and risks of optimal HCQ dosage in managing SLE.

Arthritis & Rheumatology
University of Illinois Chicago (US), Vision Eye Institute (AU), National Cheng Kung University Hospital (TW), National Cheng Kung University (TW)
Openalex Percentile: Top 11%
Drug-Induced Ocular Toxicity
1.71
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