Survival patterns and mutation profiles in never- and light-smokers with stage IV NSCLC
Never and light smokers with stage IV NSCLC displayed distinct features. The high prevalence of actionable EGFR alterations underscores the importance of comprehensive molecular testing. Region-specific data should inform precision oncology strategies and the design of prospective trials targeting non-traditional risk groups.
Authors
- Marwa Al-Shatti
- Zaid El Omari
- Karam Maraqa
- Kholoud Alqasem (ORCID: https://orcid.org/0000-0001-5766-0710)
- Salsabeel Aljawabrah
- Ala’aldin Eqleem
- Sakhr Alshwayyat
- Bayan Sheikh Ali
- Shahed Al-atiyat
- Aysheh Al-Khawaja
- Mohammad Abu Shattal (ORCID: https://orcid.org/0009-0003-7551-6239)
- Alaa BanyAmer
- Rana Elmalahi
- Sumaiah Alnaimat
- Ahmad BanyAmer
- Rahaf Turab
Institutions
- University of Jordan (JO)
- Applied Science Private University (JO)
- Jordan University of Science and Technology (JO)
- King Hussein Cancer Center (JO)
- Kern Medical Center (US)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s12885-025-15333-z
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00