Survival patterns and mutation profiles in never- and light-smokers with stage IV NSCLC

Never and light smokers with stage IV NSCLC displayed distinct features. The high prevalence of actionable EGFR alterations underscores the importance of comprehensive molecular testing. Region-specific data should inform precision oncology strategies and the design of prospective trials targeting non-traditional risk groups.

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Publication Details

Journal
BMC Cancer
Published
2025-12-22
DOI
https://doi.org/10.1186/s12885-025-15333-z
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Survival patterns and mutation profiles in never- and light-smokers with stage IV NSCLC

Marwa Al-Shatti, Zaid El Omari, Karam Maraqa, Kholoud Alqasem et al.
BMC Cancer
Lung Cancer Treatments and Mutations
article

Survival patterns and mutation profiles in never- and light-smokers with stage IV NSCLC

Marwa Al-Shatti, Zaid El Omari, Karam Maraqa, Kholoud Alqasem, Salsabeel Aljawabrah, Ala’aldin Eqleem, Sakhr Alshwayyat, Bayan Sheikh Ali, Shahed Al-atiyat, Aysheh Al-Khawaja, Mohammad Abu Shattal, Alaa BanyAmer, Rana Elmalahi, Sumaiah Alnaimat, Ahmad BanyAmer, Rahaf Turab
article en

Abstract

Never and light smokers with stage IV NSCLC displayed distinct features. The high prevalence of actionable EGFR alterations underscores the importance of comprehensive molecular testing. Region-specific data should inform precision oncology strategies and the design of prospective trials targeting non-traditional risk groups.

BMC CancerVol. 25(1)
University of Jordan (JO), Applied Science Private University (JO), Jordan University of Science and Technology (JO), King Hussein Cancer Center (JO), Kern Medical Center (US)
Good health and well-being
Openalex Percentile: Top 29%
Lung Cancer Treatments and Mutations
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Survival patterns and mutation profiles in never- and light-smokers with stage IV NSCLC — Marwa Al-Shatti, Zaid El Omari, et al. · BMC Cancer (2025) | TGRS Research Map | TGRS