Exploratory analysis of gene aberrations and chemotherapy response: findings from a real-world database in Japan
While genetic alterations alone did not outperform tumor origin as a predictor, incorporating both may improve exploratory predictions of chemotherapy response. These exploratory findings require prospective validation before any clinical application.
Authors
- Masanori Tokunaga (ORCID: https://orcid.org/0000-0002-3183-349X)
- Takashi Kamatani (ORCID: https://orcid.org/0000-0001-7164-0513)
- Sadakatsu Ikeda (ORCID: https://orcid.org/0000-0003-1629-7171)
- Satoru Aoyama
- Yusuke Kinugasa
- Naoya Ishibashi
Institutions
- Tokyo Institute of Technology (JP)
- The Cancer Institute Hospital (JP)
- Institute of Science Tokyo (JP)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1038/s41416-025-03281-1
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00