Report on the Latin American Hematopoietic Stem Cell Transplantation in Inborn Errors of Immunity Group’s Activities: Bringing Us Together!

Introduction The Latin American Hematopoietic Stem Cell Transplantation (HSCT) in Inborn Errors of Immunity (IEIs) Group (GLATEII) was established at the 2023 Latin American Society for Immunodeficiencies (LASID) meeting in Mexico. Its goal is to unite Latin American immunologists and transplant specialists. We agreed to hold monthly meetings to discuss HSCT issues in IEIs, develop guidelines, and conduct multicenter reports on HSCT in IEIs. This report summarizes GLATEII’s activities. Results To date, GLATEII has held 19 online meetings, one each month. Since February 2024, these meetings have been hosted and recorded by LASID. A total of 12 recordings are available up to April 2025, with an average of 23 participants per meeting (range 12–30). Attendees mainly include pediatric and adult immunologists and transplant specialists, along with infectologists and hematologists. Participants represent 38 institutions across 11 countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Germany, Mexico, Paraguay, Peru, Uruguay, and the USA. Topics discussed include local experiences with HSCT for IEIs, case discussions, post-HSCT immune reconstitution, post-HSCT vaccination, and HSCT in specific IEIs. Regional concerns such as “transplante social,” Bacillus Calmette–Guérin vaccination issues, IEI awareness gaps, financial shortages for treatments or studies, and access disparities have also been addressed. GLATEII has conducted multicenter reports on specific IEIs, one of which will be presented at LASID 2025. Conclusion GLATEII has successfully maintained monthly meetings focused on HSCT in IEIs from a Latin American perspective, highlighting regional similarities and differences. These gatherings promote advances in diagnosis, treatment, and transplant techniques while strengthening regional and international networks of healthcare professionals. We invite all LASID members to expand and continue these valuable activities.