Causal neurodevelopmental origins of scoliosis: Multi-omics Mendelian randomization reveals brain–region–specific pathways and protein mediators
Clinically, the results support the implementation of scoliosis screening programs in children recovering from CNS infections.
Authors
- Majid Nisar
- Xiaolei Zhang (ORCID: https://orcid.org/0000-0003-0117-7599)
- Xiangxiang Pan (ORCID: https://orcid.org/0000-0001-6555-0941)
- Chongan Huang
- Lue Liu
- Xiangyang Wang
- Aimin Wu
- Chenglong Xie
- Shuhao Zhang
- Sisi Lu
- Dongdong Xia
- Shiyu Chen
Institutions
- Wenzhou Medical University (CN)
- University of Swat (PK)
- Ruian People's Hospital (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Ningbo No. 2 Hospital (CN)
- Zhejiang Institute of Communications (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1016/j.jot.2025.09.010
- Primary Topic
- Scoliosis diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00