Molecular mechanism of RBM15-mediated m6A modification in hepatitis B virus replication

RBM15 enhances HBV replication by promoting the binding of HULC to ELAVL1 through m6A modification, and increasing BRD4 expression.

Authors

Kun Ma (ORCID: https://orcid.org/0000-0002-4256-0570)
Bingbing Li (ORCID: https://orcid.org/0000-0003-0531-4335)
Lingli Wang (ORCID: https://orcid.org/0000-0003-2756-5346)
Shengju Ma
Min Ni

Institutions

Third Affiliated Hospital of Zhengzhou University (CN)

Publication Details

Journal: Virology Journal
Published: 2025-12-22
DOI: https://doi.org/10.1186/s12985-025-03008-x
Primary Topic: RNA modifications and cancer
Type: article
Field-Weighted Citation Impact: 0.00

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article

Molecular mechanism of RBM15-mediated m6A modification in hepatitis B virus replication

Kun Ma, Bingbing Li, Lingli Wang, Shengju Ma et al.

Dec 22, 2025

Virology Journal

RNA modifications and cancer

article

Molecular mechanism of RBM15-mediated m6A modification in hepatitis B virus replication

Kun Ma, Bingbing Li, Lingli Wang, Shengju Ma, Min Ni

December 22, 2025article en

Abstract

RBM15 enhances HBV replication by promoting the binding of HULC to ELAVL1 through m6A modification, and increasing BRD4 expression.

Virology JournalVol. 22(1)

Third Affiliated Hospital of Zhengzhou University (CN)

Good health and well-being

Openalex Percentile: Top 37%

RNA modifications and cancer

DOI Open Access PDF OpenAlex

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Molecular mechanism of RBM15-mediated m6A modification in hepatitis B virus replication — Kun Ma, Bingbing Li, et al. · Virology Journal (2025) | TGRS Research Map | TGRS