Digital Technologies in Diagnosing Solitary Median Maxillary Central Incisor Syndrome

Solitary Median Maxillary Central Incisor Syndrome is unique congenital developmental defect affecting midline structures of the head and the body. The prevalent symptom is a solitary median incisor of the maxilla in primary and secondary dentition, which is positioned exactly in the midline of the alveolus. Other abnormalities that are characteristic of the syndrome include holoprosencephaly, nasal cavity anomalies, cleft palate-lip, hypotelorism, and microcephaly. It is estimated to occur in 1:50,000 live births, with female gender predilection. The cause of the syndrome is related to midline defects in the migration and connection of the prechordal mesoderm between the 35th and 38th days post-conception. Early diagnosis of SMMCI is important for practicing orthodontists, as it may be a symptom of other developmental abnormalities. The aim of this study is to report a case of SMMCI syndrome in a patient treated in the Department of Orthodontics and Facial Malformation of the University of Medical Sciences in Poznan.

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Journal
Children
Published
2025-12-20
DOI
https://doi.org/10.3390/children13010011
Primary Topic
dental development and anomalies
Type
article
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article

Digital Technologies in Diagnosing Solitary Median Maxillary Central Incisor Syndrome

K Cieślińska, Katarzyna Zaborowicz, Barbara Biedziak, Karolina Karbowska
Children
dental development and anomalies
article

Digital Technologies in Diagnosing Solitary Median Maxillary Central Incisor Syndrome

K Cieślińska, Katarzyna Zaborowicz, Barbara Biedziak, Karolina Karbowska
article en

Abstract

Solitary Median Maxillary Central Incisor Syndrome is unique congenital developmental defect affecting midline structures of the head and the body. The prevalent symptom is a solitary median incisor of the maxilla in primary and secondary dentition, which is positioned exactly in the midline of the alveolus. Other abnormalities that are characteristic of the syndrome include holoprosencephaly, nasal cavity anomalies, cleft palate-lip, hypotelorism, and microcephaly. It is estimated to occur in 1:50,000 live births, with female gender predilection. The cause of the syndrome is related to midline defects in the migration and connection of the prechordal mesoderm between the 35th and 38th days post-conception. Early diagnosis of SMMCI is important for practicing orthodontists, as it may be a symptom of other developmental abnormalities. The aim of this study is to report a case of SMMCI syndrome in a patient treated in the Department of Orthodontics and Facial Malformation of the University of Medical Sciences in Poznan.

ChildrenVol. 13(1)
Poznan University of Medical Sciences (PL)
Openalex Percentile: Top 37%
dental development and anomalies
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Digital Technologies in Diagnosing Solitary Median Maxillary Central Incisor Syndrome — K Cieślińska, Katarzyna Zaborowicz, et al. · Children (2025) | TGRS Research Map | TGRS