In Vivo Volumetric Analysis of Endolymphatic Hydrops in Ménière Disease Using 7-Tesla MRI and Advanced Post-Processing
In vivo 7T MRI volumetry revealed significantly greater EH in the utricle and SCC of MD-affected ears versus controls, demonstrating its utility for characterizing EH and guiding more precise diagnostics and therapies. Future work must refine methods to reliably distinguish the utricle-saccule boundary-through improved imaging protocols or automated segmentation-to assess saccular hydrops in living patients.
Authors
- Adrian Paez (ORCID: https://orcid.org/0000-0003-0225-4453)
- Joon Soo Kim (ORCID: https://orcid.org/0000-0001-5222-1452)
- ANDY DING
- Yinghao Li (ORCID: https://orcid.org/0000-0001-7972-6573)
- Jun Hua (ORCID: https://orcid.org/0000-0001-5481-7380)
- Syed Ameen Ahmad (ORCID: https://orcid.org/0000-0002-6179-5252)
- Bryan K. Ward
- John P. Carey
- Yuanqi Sun
- Diane Jung
- Francis Deng
Institutions
- Kennedy Krieger Institute (US)
- Johns Hopkins University (US)
- University of Miami (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Otology & Neurotology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1097/mao.0000000000004779
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00