Scalp‐negative medial temporal interictal epileptic discharges alter large‐scale brain networks: A simultaneous high‐density <scp>electroencephalographic</scp> and intracranial <scp>electroencephalographic</scp> study
Despite being localized in medial temporal regions, these IEDs have a widespread impact on functional brain networks, potentially contributing to cognitive impairment in epilepsy. This study lays the groundwork for examining their real-time effects on cognition, including in neurodegenerative conditions such as Alzheimer disease, where these IEDs can be present and difficult to detect.
Authors
- Nicolas Roehri (ORCID: https://orcid.org/0000-0002-6948-1055)
- L. Spinelli
- Pia De Stefano (ORCID: https://orcid.org/0000-0002-7979-0994)
- Stanislas Lagarde (ORCID: https://orcid.org/0000-0003-2916-1302)
- Serge Vulliémoz (ORCID: https://orcid.org/0000-0002-1877-8625)
- Shahan Momjian (ORCID: https://orcid.org/0000-0002-3886-0159)
- Renaud Marquis (ORCID: https://orcid.org/0000-0002-1145-242X)
- Margitta Seeck
Institutions
- University of Geneva (CH)
- Inserm (FR)
- University Hospital of Geneva (CH)
- Institut de Neurosciences des Systèmes (FR)
- Centre d'Imagerie BioMedicale (CH)
- Geneva College (US)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1002/epi.70061
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00